Significant reduction of sperm disomy in six men: effect of traditional Chinese medicine?

Tempest HG et al, Asian J Androl. 2005 Vol 7(4):419-25.
Asian Journal of Andrology.

This is a small pilot study carried out in the UK, but one of the few (outside of China)  to look at the effect of Chinese herbs on sperm quality. The incidence of chromosomal abnormality in all the patients who took the herbs was significantly reduced. Further trials are needed to confirm these findings. 


Aim: To test the hypothesis that levels of sperm disomy fell significantly in six men treated by traditional Chinese medicine (TCM).

Methods: Fluorescence in situ hybridization (FISH) was done on the sperm heads of six men before and during treatment by TCM.

Results: There was a significant reduction in sperm disomy in all six men. This coincided with TCM treatment.

Conclusion: This is the first study reporting a significant reduction in sperm disomy in men over a given time course. The fact that this coincided with TCM treatment is intriguing but no conclusions can be drawn from this until placebo-controlled clinical trials are implemented.