Clinical study on effect of Bushen Huayu Qutan Recipe in treating polycystic ovarian syndrome

Wu JH et al, Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Oct;27(10):883-6 Chinese Journal of Integrated Traditional and Western medicine   
A Kidney tonic formula was tested on PCOS patients after it had been shown to be effective in reducing testosterone and insulin and promoting ovulation in sterilised rats. PCOS patients took the formula for 6 months - it was effective in reducing obesity and acne as well as insulin and testosterone levels.



Objective: To investigate the therapeutic effect and the possible mechanism of Bushen Huayu Qutan Recipe (BHQR, a Chinese recipe formulated according to the therapeutic principle of nourishing Shen, resolving stasis and dispelling phlegm) on polycystic ovarian syndrome (PCOS).

Methods: BHQR was used, both internally and externally, to treat 46 patients with PCOS, and combined with diformin if necessary. Six successive months treatment was regarded as one course. The clinical symptoms and signs, including obesity, polytrichia, acne and acanthosis, were observed and scored before and after treatment; and serum levels of hormones and insulin were measured as well.

Results: After treatment, the scores of symptoms and signs of patients were significantly lowered (P<0.05 for obesity and P <0.01 for others), significant lowering was also found in serum level of testosterone (P<0.05), fasting serum insulin (P<0.01) and the values of insulin and insulin area under curve (P<0.05) 30 min and 60 min after glucose load.

Conclusion: BHQR could not only significantly relieve the symptoms and signs of patients with PCOS, but also regulate well the ovarian function.